These two studies show how low-level laser therapy (LLLT) can regenerate damaged nerves, treating the root of problems that cause nerve pain.

Many people living with nerve damage and pain have been told that their symptoms are permanent, and can only be masked using medication. However, recent landmark studies have shown that low-level laser therapy (LLLT) can regenerate damaged nerves in many circumstances, treating the root of the problem that’s causing the symptoms.

Here is an overview of two of the studies that provide compelling evidence for LLLT’s pain reduction benefits.

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Study: 200 Patients with Diabetic Peripheral Neuropathy2

A single-blinded randomised controlled trial, published in 2025, studied a group of 200 Type 2 diabetes patients with diabetic peripheral neuropathy, a common form of nerve damage, affecting their hands and feet.

  • The intervention group received LLLT (photobiomodulation).
  • The control group received placebo laser treatments.

The intervention group showed the following results when the patients were assessed after four weeks:

  • Pain intensity: Reduced by 53%.
  • Neuropathy symptoms: Improved 52%.
  • Nerve function: Improved 33%.
  • Quality of life: Improved 68%.

(vs no meaningful change in the control group)

The study found that “Photobiomodulation therapy proved effective in reducing neuropathic pain and associated symptoms, leading to an improved quality of life for DPN patients.”

Download the coMra e-book for more information on coMra therapy

Study: 110 Patients with Lumbar Radiculopathy1

A double-blind randomised controlled trial, published in 2022, studied a total of 110 participants with acute lower back pain and nerve damage caused by a herniated disc.

The participants were randomly assigned into two groups of 55 each.

  • The experimental group was treated with LLLT and conventional physical therapy.
  • The control group was treated with conventional physical therapy only. Both groups received 18 treatment sessions.

Both groups showed improvement; however, the experimental group showed greater improvement than the control group. Results using a combination of LLLT and physical therapy were as follows:

  • Pain intensity: Reduced by 86%.
  • Functional disability: Improved 47%.
  • Range of motion: Forward bending ability increased 28%.
  • Nerve tension signs: 98% resolved.

Join our Neuropathy Webinar: Overcoming Nerve Damage

Our upcoming webinar, scheduled for December 9 and presented by coMra therapy educator Garrett Murrin, will unpack these studies and more. This webinar is ideal for those living with painful nerve damage, including:

  • Diabetic neuropathy.
  • Post-surgical nerve damage.
  • Idiopathic neuropathy (unknown cause).
  • Infectious neuropathy (shingles, Lyme disease, herpes zoster).
  • Nutritional or alcoholic neuropathy.
  • Trigeminal neuralgia or facial nerve damage.
  • Any condition where you’ve been told “the damage is permanent”.

Book your seat at this FREE live webinar to find out what’s possible with LLLT.

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References:

1 Ahmed I, Bandpei MAM, Gilani SA, Ahmad A, Zaidi F. Effectiveness of low-level laser therapy in patients with discogenic lumbar radiculopathy: a double-blind randomized controlled trial. J Healthc Eng. 2022;2022:6437523. doi:10.1155/2022/6437523.2 Anju M, Ummer Velladath S, Arun Maiya G, et al. A single blinded randomized controlled trial assessing the effect of photobiomodulation therapy on neuron specific biomarkers in type II diabetes mellitus patients with peripheral neuropathy. Diabetes Res Clin Pract. 2025;222:112087. doi:10.1016/j.diabres.2025.1120873 Karagözoğlu İ, Demirkol N, Parlar Öz Ö, et al. Clinical efficacy of two different low-level laser therapies for the treatment of trigeminal neuralgia: a randomized, placebo-controlled trial. J Clin Med. 2024;13(22):6890. doi:10.3390/jcm13226890.4 coMra User Guide.